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Fragile X-Associated Diminished Ovarian Reserve and Primary Ovarian Insufficiency from Molecular Mechanisms to Clinical Manifestations

Fragile X syndrome (FXS), is caused by a loss-of-function mutation in the FMR1 gene located on the X-chromosome, which leads to the most common cause of inherited intellectual disability in males and the leading single-gene defect associated with autism. A full mutation (FM) is represented by more t...

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Publicado en:Front Mol Neurosci
Autores principales: Man, Limor, Lekovich, Jovana, Rosenwaks, Zev, Gerhardt, Jeannine
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600956/
https://ncbi.nlm.nih.gov/pubmed/28955201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00290
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