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Deciphering the Pathogenesis of Human Type 1 Diabetes (T1D) by Interrogating T Cells from the “Scene of the Crime”

PURPOSE OF REVIEW: Autoimmune-mediated destruction of insulin-producing β-cells within the pancreas results in type 1 diabetes (T1D), which is not yet preventable or curable. Previously, our understanding of the β-cell specific T cell repertoire was based on studies of autoreactive T cell responses...

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Pubblicato in:Curr Diab Rep
Autori principali: Kent, Sally C., Mannering, Stuart I., Michels, Aaron W., Babon, Jenny Aurielle B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600889/
https://ncbi.nlm.nih.gov/pubmed/28864875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11892-017-0915-y
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