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Patient-derived interstitial fluids and predisposition to aggressive sporadic breast cancer through collagen remodeling and inactivation of p53

BACKGROUND: Despite the fact that interstitial fluid (IF) represents a third of our body fluid, it is the most poorly understood body fluid in medicine. Increased IF pressure is thought to result from the increased deposition of extracellular matrix in the affected tissue preventing its reabsorption...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Kenny, Timothy, Schmidt, Hank, Adelson, Kerin, Hoshida, Yujin, Koh, Anna P., Shah, Nagma, Mandeli, John, Ting, Jess, Germain, Doris
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600839/
https://ncbi.nlm.nih.gov/pubmed/28630214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0342
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