Age and gender associations of virus positivity in Merkel cell carcinoma characterized using a novel RNA in situ hybridization assay

PURPOSE: Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine tumor of the skin. Merkel cell polyomavirus (MCPyV) plays an oncogenic role in the majority of MCCs. Detection of MCPyV in MCCs has diagnostic utility and prognostic potential. We investigated whether RNAscope, an RNA in situ...

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Publicado no:Clin Cancer Res
Main Authors: Wang, Lisha, Harms, Paul W., Palanisamy, Nallasivam, Carskadon, Shannon, Cao, Xuhong, Siddiqui, Javed, Patel, Rajiv M., Zelenka-Wang, Sylvia, Durham, Alison B., Fullen, Douglas R., Harms, Kelly L., Su, Fengyun, Shukla, Sudhanshu, Mehra, Rohit, Chinnaiyan, Arul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600832/
https://ncbi.nlm.nih.gov/pubmed/28606924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0299
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