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Modeling the Cellular Response of Lung Cancer to Radiation Therapy for a Broad Range of Fractionation Schedules

PURPOSE: To demonstrate that a mathematical model can be used to quantitatively understand tumor cellular dynamics during a course of radiotherapy, and to predict the likelihood of local control as a function of dose and treatment fractions. EXPERIMENTAL DESIGN: We model outcomes for early-stage, lo...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Jeong, Jeho, Oh, Jung Hun, Sonke, Jan-Jakob, Belderbos, Jose, Bradley, Jeffrey D., Fontanella, Andrew N., Rao, Shyam S., Deasy, Joseph O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600831/
https://ncbi.nlm.nih.gov/pubmed/28539466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-3277
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