Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis

The microbiome can promote or disrupt human health by influencing both adaptive and innate immune functions. We tested whether bacteria that normally reside on human skin participate in host defense by killing Staphylococcus aureus, a pathogen commonly found in patients with atopic dermatitis (AD) a...

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Udgivet i:Sci Transl Med
Main Authors: Nakatsuji, Teruaki, Chen, Tiffany H., Narala, Saisindhu, Chun, Kimberly A., Two, Aimee M., Yun, Tong, Shafiq, Faiza, Kotol, Paul F., Bouslimani, Amina, Melnik, Alexey V., Latif, Haythem, Kim, Ji-Nu, Lockhart, Alexandre, Artis, Keli, David, Gloria, Taylor, Patricia, Streib, Joanne, Dorrestein, Pieter C., Grier, Alex, Gill, Steven R., Zengler, Karsten, Hata, Tissa R., Leung, Donald Y. M., Gallo, Richard L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600545/
https://ncbi.nlm.nih.gov/pubmed/28228596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aah4680
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