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Flavaglines Ameliorate Experimental Colitis and Protect Against Intestinal Epithelial Cell Apoptosis and Mitochondrial Dysfunction

BACKGROUND: Flavaglines are a family of natural compounds shown to have anti-inflammatory and cytoprotective effects in neurons and cardiomyocytes. Flavaglines target prohibitins as ligands, which are scaffold proteins that regulate mitochondrial function, cell survival, and transcription. This stud...

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發表在:Inflamm Bowel Dis
Main Authors: Han, Jie, Zhao, Qian, Basmadjian, Christine, Désaubry, Laurent, Theiss, Arianne L.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600465/
https://ncbi.nlm.nih.gov/pubmed/26398710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000592
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