Conditional deletion of CD98hc inhibits osteoclast development

The CD98 heavy chain (CD98hc) regulates virus-induced cell fusion and monocyte fusion, and is involved in amino acid transportation. Here, we examined the role that CD98hc plays in the formation of osteoclasts using CD98hc(flox/flox)LysM-cre peritoneal macrophages (CD98hc-defect macrophages). Perito...

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Veröffentlicht in:Biochem Biophys Rep
Hauptverfasser: Tsumura, Hideki, Ito, Morihiro, Takami, Masamichi, Arai, Miyuki, Li, Xiao-Kang, Hamatani, Toshio, Igarashi, Arisa, Takada, Shuji, Miyado, Kenji, Umezawa, Akihiro, Ito, Yasuhiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600448/
https://ncbi.nlm.nih.gov/pubmed/28955825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.11.023
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