DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates

Well-known epigenetic DNA modifications in mammals include the addition of a methyl group and a hydroxyl group to cytosine, resulting in 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) respectively. In contrast, the abundance and the functional implications of these modifications in invert...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Rasmussen, Erik M.K., Vågbø, Cathrine B., Münch, Daniel, Krokan, Hans E., Klungland, Arne, Amdam, Gro V., Dahl, John Arne
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600429/
https://ncbi.nlm.nih.gov/pubmed/28955859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.02.011
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