Receptor and post-receptor abnormalities contribute to insulin resistance in myotonic dystrophy type 1 and type 2 skeletal muscle

Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are autosomal dominant multisystemic disorders caused by expansion of microsatellite repeats. In both forms, the mutant transcripts accumulate in nuclear foci altering the function of alternative splicing regulators which are necessary for the physiol...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Renna, Laura Valentina, Bosè, Francesca, Iachettini, Sara, Fossati, Barbara, Saraceno, Lorenzo, Milani, Valentina, Colombo, Roberto, Meola, Giovanni, Cardani, Rosanna
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600405/
https://ncbi.nlm.nih.gov/pubmed/28915272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184987
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker