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Binding of canonical Wnt ligands to their receptor complexes occurs in ordered plasma membrane environments

While the cytosolic events of Wnt/β‐catenin signaling (canonical Wnt signaling) pathway have been widely studied, only little is known about the molecular mechanisms involved in Wnt binding to its receptors at the plasma membrane. Here, we reveal the influence of the immediate plasma membrane enviro...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Sezgin, Erdinc, Azbazdar, Yagmur, Ng, Xue W., Teh, Cathleen, Simons, Kai, Weidinger, Gilbert, Wohland, Thorsten, Eggeling, Christian, Ozhan, Gunes
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599997/
https://ncbi.nlm.nih.gov/pubmed/28626941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14139
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