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The Translesion Polymerase Pol η Is Required for Efficient Epstein-Barr Virus Infectivity and Is Regulated by the Viral Deubiquitinating Enzyme BPLF1

Epstein-Barr virus (EBV) infection and lytic replication are known to induce a cellular DNA damage response. We previously showed that the virally encoded BPLF1 protein interacts with and regulates several members of the translesion synthesis (TLS) pathway, a DNA damage tolerance pathway, and that t...

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Vydáno v:J Virol
Hlavní autoři: Dyson, Ossie F., Pagano, Joseph S., Whitehurst, Christopher B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599766/
https://ncbi.nlm.nih.gov/pubmed/28724765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00600-17
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