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Formulation and evaluation of carnosic acid nanoparticulate system for upregulation of neurotrophins in the brain upon intranasal administration

To develop formulations of carnosic acid nanoparticles and to assess their in vivo efficacy to enhance the expression of neurotrophins in rat model. Carnosic acid loaded chitosan nanoparticles were prepared by ionotropic gelation technique using central composite design. Response surface methodology...

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書目詳細資料
發表在:J Drug Target
Main Authors: Vaka, Siva Ram Kiran, Shivakumar, H.N., Repka, Michael A., Murthy, S. Narasimha
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599709/
https://ncbi.nlm.nih.gov/pubmed/23020597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1061186X.2012.725405
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