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Brain barriers and functional interfaces with sequential appearance of ABC efflux transporters during human development

Adult brain is protected from entry of drugs and toxins by specific mechanisms such as ABC (ATP-binding Cassette) efflux transporters. Little is known when these appear in human brain during development. Cellular distribution of three main ABC transporters (ABCC1, ABCG2, ABCB1) was determined at blo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Møllgård, Kjeld, Dziegielewska, Katarzyna M., Holst, Camilla B., Habgood, Mark D., Saunders, Norman R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599687/
https://ncbi.nlm.nih.gov/pubmed/28912477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11596-0
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