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Matrisome Profiling During Intervertebral Disc Development And Ageing

Intervertebral disc (IVD) degeneration is often the cause of low back pain. Degeneration occurs with age and is accompanied by extracellular matrix (ECM) depletion, culminating in nucleus pulpous (NP) extrusion and IVD destruction. The changes that occur in the disc with age have been under investig...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Caldeira, Joana, Santa, Cátia, Osório, Hugo, Molinos, Maria, Manadas, Bruno, Gonçalves, Raquel, Barbosa, Mário
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599645/
https://ncbi.nlm.nih.gov/pubmed/28912585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11960-0
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