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Vimentin knockout results in increased expression of sub-endothelial basement membrane components and carotid stiffness in mice

Intermediate filaments are involved in stress-related cell mechanical properties and in plasticity via the regulation of focal adhesions (FAs) and the actomyosin network. We investigated whether vimentin regulates endothelial cells (ECs) and vascular smooth muscle cells (SMCs) and thereby influences...

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Vydáno v:Sci Rep
Hlavní autoři: Langlois, Benoit, Belozertseva, Ekaterina, Parlakian, Ara, Bourhim, Mustapha, Gao-Li, Jacqueline, Blanc, Jocelyne, Tian, Lei, Coletti, Dario, Labat, Carlos, Ramdame-Cherif, Zhor, Challande, Pascal, Regnault, Véronique, Lacolley, Patrick, Li, Zhenlin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599644/
https://ncbi.nlm.nih.gov/pubmed/28912461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12024-z
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