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Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography

Extracellular vesicles (EVs) play a pivotal role in cell-to-cell communication and have been shown to take part in several physiological and pathological processes. EVs have traditionally been purified by ultracentrifugation (UC), however UC has limitations, including resulting in, operator-dependan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Corso, Giulia, Mäger, Imre, Lee, Yi, Görgens, André, Bultema, Jarred, Giebel, Bernd, Wood, Matthew J. A., Nordin, Joel Z., Andaloussi, Samir EL
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599601/
https://ncbi.nlm.nih.gov/pubmed/28912498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10646-x
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