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Iron deposition is associated with differential macrophage infiltration and therapeutic response to iron chelation in prostate cancer

Immune cells such as macrophages are drivers and biomarkers of most cancers. Scoring macrophage infiltration in tumor tissue provides a prognostic assessment that is correlated with disease outcome and therapeutic response, but generally requires invasive biopsy. Routine detection of hemosiderin iro...

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Publicat a:Sci Rep
Autors principals: Leftin, Avigdor, Zhao, Huiyong, Turkekul, Mesru, de Stanchina, Elisa, Manova, Katia, Koutcher, Jason A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599545/
https://ncbi.nlm.nih.gov/pubmed/28912459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11899-2
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