A Brucella Type IV effector targets the COG tethering complex to remodel host secretory traffic and promote intracellular replication

Many intracellular pathogens exploit host secretory trafficking to support their intracellular cycle, but knowledge of these pathogenic processes is limited. The bacterium Brucella abortus uses a Type IV secretion system (VirB T4SS) to generate a replication-permissive Brucella-containing vacuole (r...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Miller, Cheryl N., Smith, Erin P., Cundiff, Jennifer A., Knodler, Leigh A., Blackburn, Jessica Bailey, Lupashin, Vladimir, Celli, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599354/
https://ncbi.nlm.nih.gov/pubmed/28844886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.07.017
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