A Brucella Type IV effector targets the COG tethering complex to remodel host secretory traffic and promote intracellular replication

Many intracellular pathogens exploit host secretory trafficking to support their intracellular cycle, but knowledge of these pathogenic processes is limited. The bacterium Brucella abortus uses a Type IV secretion system (VirB T4SS) to generate a replication-permissive Brucella-containing vacuole (r...

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發表在:Cell Host Microbe
Main Authors: Miller, Cheryl N., Smith, Erin P., Cundiff, Jennifer A., Knodler, Leigh A., Blackburn, Jessica Bailey, Lupashin, Vladimir, Celli, Jean
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599354/
https://ncbi.nlm.nih.gov/pubmed/28844886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.07.017
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