Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer

IMPORTANCE: Germline pathogenic variants in BRCA1 and BRCA2 predispose to an increased lifetime risk of breast cancer. However, the relevance of germline variants in other genes from multigene hereditary cancer testing panels is not well defined. OBJECTIVE: To determine the risks of breast cancer as...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Couch, Fergus J., Shimelis, Hermela, Hu, Chunling, Hart, Steven N., Polley, Eric C., Na, Jie, Hallberg, Emily, Moore, Raymond, Thomas, Abigail, Lilyquist, Jenna, Feng, Bingjian, McFarland, Rachel, Pesaran, Tina, Huether, Robert, LaDuca, Holly, Chao, Elizabeth C., Goldgar, David E., Dolinsky, Jill S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599323/
https://ncbi.nlm.nih.gov/pubmed/28418444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2017.0424
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