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Nanoparticle-releasing nanofiber composites for enhanced in vivo vaginal retention

Current approaches for topical vaginal administration of nanoparticles result in poor retention and extensive leakage. To overcome these challenges, we developed a nanoparticle-releasing nanofiber delivery platform and evaluated its ability to improve nanoparticle retention in a murine model. We ind...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Krogstad, Emily A., Ramanathan, Renuka, Nhan, Christina, Kraft, John C., Blakney, Anna K., Cao, Shijie, Ho, Rodney J. Y., Woodrow, Kim A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599218/
https://ncbi.nlm.nih.gov/pubmed/28802690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.07.034
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