Clinical Management of Potential Toxicities and Drug Interactions Related to Cyclin‐Dependent Kinase 4/6 Inhibitors in Breast Cancer: Practical Considerations and Recommendations

Aberrations of the cell cycle are pervasive in cancer, and selective cell cycle inhibition of cancer cells is a target of choice for a number of novel cancer therapeutics. Cyclin‐dependent kinases (CDKs) are key regulatory enzymes that control cell cycle transitions and the commitment to cell divisi...

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Bibliographic Details
Published in:Oncologist
Main Authors: Spring, Laura M., Zangardi, Mark L., Moy, Beverly, Bardia, Aditya
Format: Artigo
Language:Inglês
Published: AlphaMed Press 2017
Subjects:
Breast Cancer
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599204/
https://ncbi.nlm.nih.gov/pubmed/28706010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0142
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