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Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase

DHHC enzymes catalyze palmitoylation, a major post-translational modification that regulates a number of key cellular processes. There are up to 24 DHHCs in mammals and hundreds of substrate proteins that get palmitoylated. However, how DHHC enzymes engage with their substrates is still poorly under...

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Bibliographic Details
Published in:Structure
Main Authors: Verardi, Raffaello, Kim, Jin-Sik, Ghirlando, Rodolfo, Banerjee, Anirban
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599134/
https://ncbi.nlm.nih.gov/pubmed/28757145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.06.018
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