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Expression of TLR2, NOD1 and NOD2 and the NLRP3 inflammasome in renal tubular epithelial cells of male versus female mice

BACKGROUND: Sex biased outcomes are associated with acute kidney injury (AKI) and human and animal studies have shown females are preferentially protected from renal ischemia. Why females are protected is not known. One clue might lie with pattern recognition receptors (PRRs), which are triggers of...

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Publicat a:Nephron
Autors principals: DeWolf, Sean E., Shigeoka, Alana A., Scheinok, Andrew, Kasimsetty, Sashi G., Welch, Alexander K., McKay, Dianne B.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599100/
https://ncbi.nlm.nih.gov/pubmed/28614830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000456016
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