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Genotypic characterization directly applied to sputum improves the detection of Mycobacterium africanum West African 1, under-represented in positive cultures

BACKGROUND: This study aimed to compare the prevalence of Mycobacterium tuberculosis complex (MTBc) lineages between direct genotyping (on sputum) and indirect genotyping (on culture), to characterize potential culture bias against difficult growers. METHODOLOGY/PRINCIPAL FINDINGS: Smear-positive sp...

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Bibliografiske detaljer
Udgivet i:PLoS Negl Trop Dis
Main Authors: Sanoussi, C. N’Dira, Affolabi, Dissou, Rigouts, Leen, Anagonou, Séverin, de Jong, Bouke
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599059/
https://ncbi.nlm.nih.gov/pubmed/28863143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005900
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