Selective Activation of Basal Forebrain Cholinergic Neurons Attenuates Polymicrobial Sepsis–Induced Inflammation via the Cholinergic Anti-Inflammatory Pathway

OBJECTIVES: Basal forebrain cholinergic neurons are proposed as a major neuromodulatory system in inflammatory modulation. However, the function of basal forebrain cholinergic neurons in sepsis is unknown, and the neural pathways underlying cholinergic anti-inflammation remain unexplored. DESIGN: An...

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Detalhes bibliográficos
Publicado no:Crit Care Med
Main Authors: Zhai, Qian, Lai, Dengming, Cui, Ping, Zhou, Rui, Chen, Qixing, Hou, Jinchao, Su, Yunting, Pan, Libiao, Ye, Hui, Zhao, Jing-Wei, Fang, Xiangming
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
Assuntos:
Online Laboratory Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598911/
https://ncbi.nlm.nih.gov/pubmed/28806219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000002646
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