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Investigating DNA supercoiling in eukaryotic genomes

Supercoiling is a fundamental property of DNA, generated by polymerases and other DNA-binding proteins as a consequence of separating/bending the DNA double helix. DNA supercoiling plays a key role in gene expression and genome organization, but has proved difficult to study in eukaryotes because of...

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Bibliografske podrobnosti
izdano v:Brief Funct Genomics
Main Authors: Corless, Samuel, Gilbert, Nick
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598747/
https://ncbi.nlm.nih.gov/pubmed/28444308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bfgp/elx007
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