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Butafenacil: A positive control for identifying anemia- and variegate porphyria-inducing chemicals

Butafenacil is an herbicide that inhibits protoporphyrinogen oxidase (PPOX), an enzyme that catalyzes oxidation of protoporphyrinogen IX to protoporphyrin IX during chlorophyll and heme biosynthesis. Based on a high-content screen, we previously identified butafenacil as a potent inducer of anemia i...

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Publicat a:Toxicol Rep
Autors principals: Leet, Jessica K., Hipszer, Rachel A., Volz, David C.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598413/
https://ncbi.nlm.nih.gov/pubmed/28962437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2015.07.006
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