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Cytotoxic effects exerted by pentachlorophenol by targeting nodal pro-survival signaling pathways in human pancreatic cancer cells

Pancreatic adenocarcinoma is one of the deadliest human solid tumors in the developed countries characterized by high resistance toward chemotherapeutic treatment. We have previously shown that silencing of the pro-survival protein kinase CK2 by RNA interference contributes to enhance the cytotoxici...

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Publicat a:Toxicol Rep
Autors principals: Schaefer, Susanne, Kreutzer, Jan N., Issinger, Olaf-Georg, Guerra, Barbara
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598403/
https://ncbi.nlm.nih.gov/pubmed/28962326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2014.10.027
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