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Cytotoxic effects exerted by pentachlorophenol by targeting nodal pro-survival signaling pathways in human pancreatic cancer cells

Pancreatic adenocarcinoma is one of the deadliest human solid tumors in the developed countries characterized by high resistance toward chemotherapeutic treatment. We have previously shown that silencing of the pro-survival protein kinase CK2 by RNA interference contributes to enhance the cytotoxici...

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Publicado en:Toxicol Rep
Autores principales: Schaefer, Susanne, Kreutzer, Jan N., Issinger, Olaf-Georg, Guerra, Barbara
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598403/
https://ncbi.nlm.nih.gov/pubmed/28962326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2014.10.027
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