The effects of N-acetylcysteine on cisplatin-induced cardiotoxicity on isolated rat hearts after short-term global ischemia

The aim of this study was to estimate the protective effect of N-acetyl-l-cysteine (NAC) against cisplatin-induced cardiotoxicity under conditions of ischemic-reperfusion injury. Wistar albino rats were randomly divided into three groups (n = 8): control, cisplatin (5 mg/kg/w, i.p., 5 weeks) and cis...

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Bibliographic Details
Published in:Toxicol Rep
Main Authors: Rosic, Gvozden, Srejovic, Ivan, Zivkovic, Vladimir, Selakovic, Dragica, Joksimovic, Jovana, Jakovljevic, Vladimir
Format: Artigo
Language:Inglês
Published: Elsevier 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598382/
https://ncbi.nlm.nih.gov/pubmed/28962440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2015.07.009
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