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Distinct Mechanisms of Tumor Resistance to NK Killing: Of Mice and Men

Tumors cells can release natural killer (NK) cell ligands for activating receptor NKG2D that are thought to inhibit NK cell function. In a recent issue of Science, Deng et al. (2015) show that, unexpectedly, a soluble NKG2D ligand can enhance anti-tumor NK cell activity.

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Detalhes bibliográficos
Publicado no:Immunity
Autor principal: Pardoll, Drew M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598348/
https://ncbi.nlm.nih.gov/pubmed/25902479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.04.007
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