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Delivery of cefotaxime to the brain via intranasal administration

The purpose of this study was to investigate the plausibility of delivery of cefotaxime to the brain via intranasal administration. In vitro permeation studies were carried out using Franz diffusion cells, and the effect of different concentrations of chitosan (0.1% w/v and 0.25% w/v) on drug permea...

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Publicado en:Drug Dev Ind Pharm
Main Authors: Manda, Prashanth, Hargett, Jamie K., Vaka, Siva Ram Kiran, Repka, Michael A., Murthy, S. Narasimha
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598079/
https://ncbi.nlm.nih.gov/pubmed/21702731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03639045.2011.571696
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