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Tia1 dependent regulation of mRNA subcellular location and translation controls p53 expression in B cells

Post-transcriptional regulation of cellular mRNA is essential for protein synthesis. Here we describe the importance of mRNA translational repression and mRNA subcellular location for protein expression during B lymphocyte activation and the DNA damage response. Cytoplasmic RNA granules are formed u...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Díaz-Muñoz, Manuel D., Kiselev, Vladimir Yu., Le Novère, Nicolas, Curk, Tomaz, Ule, Jernej, Turner, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597594/
https://ncbi.nlm.nih.gov/pubmed/28904350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00454-2
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