Should abacavir be a first-line alternative for adults with HIV in sub-Saharan Africa?

Despite a poor toxicity profile, zidovudine supersedes abacavir as an alternative first-line agent in most international treatment-guidelines due to concerns about HLA-B(*)57:01-related abacavir-hypersensitivity. We detected one case of HLA-B(*)57:01 carriage among 513 HIV-infected individuals in Ug...

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Dades bibliogràfiques
Publicat a:J Acquir Immune Defic Syndr
Autors principals: Lee, Guinevere Q., McCluskey, Suzanne, Boum, Yap, Hunt, Peter W., Martin, Jeffrey N., Bangsberg, David R., Gao, Xiaojiang, Harrigan, P. Richard, Haberer, Jessica E., Siedner, Mark J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597467/
https://ncbi.nlm.nih.gov/pubmed/28639996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001487
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