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Aligned fibers direct collective cell migration to engineer closing and nonclosing wound gaps

Cell emergence onto damaged or organized fibrous extracellular matrix (ECM) is a crucial precursor to collective cell migration in wound closure and cancer metastasis, respectively. However, there is a fundamental gap in our quantitative understanding of the role of local ECM size and arrangement in...

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Publicat a:Mol Biol Cell
Autors principals: Sharma, Puja, Ng, Colin, Jana, Aniket, Padhi, Abinash, Szymanski, Paige, Lee, Jerry S. H., Behkam, Bahareh, Nain, Amrinder S.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597329/
https://ncbi.nlm.nih.gov/pubmed/28747440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-05-0305
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