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Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes

The efficient transport of cargoes within axons and dendrites is critical for neuronal function. Although we have a basic understanding of axonal transport, much less is known about transport in dendrites. We used an optogenetic approach to recruit motor proteins to cargo in real time within axons o...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Ayloo, Swathi, Guedes-Dias, Pedro, Ghiretti, Amy E., Holzbaur, Erika L. F.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597326/
https://ncbi.nlm.nih.gov/pubmed/28720664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-01-0068
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