Oxidative stress induces dysregulated autophagy in corneal epithelium of keratoconus patients

Oxidative stress is one of the key factors that contributes to the pathogenesis of keratoconus (KC). Macroautophagy is a vital cellular mechanism that is activated in response to oxidative stress. The aim of this study was to understand the role of the autophagic lysosomal pathway in the oxidative d...

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Veröffentlicht in:PLoS One
Hauptverfasser: Shetty, Rohit, Sharma, Anupam, Pahuja, Natasha, Chevour, Priyanka, Padmajan, Neeraja, Dhamodaran, Kamesh, Jayadev, Chaitra, M. M. A. Nuijts, Rudy, Ghosh, Arkasubhra, Nallathambi, Jeyabalan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597215/
https://ncbi.nlm.nih.gov/pubmed/28902914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184628
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