The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival

The cytoprotective protein clusterin is often dysregulated during tumorigenesis, and in the stomach, upregulation of clusterin marks emergence of the oxyntic atrophy (loss of acid-producing parietal cells)-associated spasmolytic polypeptide-expressing metaplasia (SPEM). The hormone gastrin is import...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vange, Pål, Bruland, Torunn, Doseth, Berit, Fossmark, Reidar, Sousa, Mirta M. L., Beisvag, Vidar, Sørdal, Øystein, Qvigstad, Gunnar, Waldum, Helge L., Sandvik, Arne K., Bakke, Ingunn
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597207/
https://ncbi.nlm.nih.gov/pubmed/28902909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184514
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