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Sulfated hydrogel matrices direct mitogenicity and maintenance of chondrocyte phenotype through activation of FGF signaling

Deciphering the roles of chemical and physical features of the extracellular matrix (ECM) is vital for developing biomimetic materials with desired cellular responses in regenerative medicine. Here, we demonstrate that sulfation of biopolymers, mimicking the proteoglycans in native tissues, induces...

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Detalles Bibliográficos
Publicado en:Adv Funct Mater
Main Authors: Öztürk, Ece, Arlov, Øystein, Aksel, Seda, Li, Ling, Ornitz, David M., Skjåk-Bræk, Gudmund, Zenobi-Wong, Marcy
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597002/
https://ncbi.nlm.nih.gov/pubmed/28919847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.201600092
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