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Sulfated hydrogel matrices direct mitogenicity and maintenance of chondrocyte phenotype through activation of FGF signaling

Deciphering the roles of chemical and physical features of the extracellular matrix (ECM) is vital for developing biomimetic materials with desired cellular responses in regenerative medicine. Here, we demonstrate that sulfation of biopolymers, mimicking the proteoglycans in native tissues, induces...

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Detalhes bibliográficos
Publicado no:Adv Funct Mater
Main Authors: Öztürk, Ece, Arlov, Øystein, Aksel, Seda, Li, Ling, Ornitz, David M., Skjåk-Bræk, Gudmund, Zenobi-Wong, Marcy
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597002/
https://ncbi.nlm.nih.gov/pubmed/28919847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.201600092
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