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Ethanol Exposure Regulates Gabra1 Expression via Histone Deacetylation at the Promoter in Cultured Cortical Neurons

γ-Aminobutyric acid A receptors (GABA(A)-Rs) mediate the majority of inhibitory neurotransmission in the adult brain. The α1-containing GABA(A)-Rs are the most prominent subtype in the adult brain and are important in both homeostatic function and several disease pathologies including alcohol depend...

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Bibliographische Detailangaben
Veröffentlicht in:J Pharmacol Exp Ther
Hauptverfasser: Bohnsack, John Peyton, Patel, Vraj K., Morrow, A. Leslie
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596976/
https://ncbi.nlm.nih.gov/pubmed/28798030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.242446
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