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The combination of recombinant and non-recombinant Bacillus subtilis spore display technology for presentation of antigen and adjuvant on single spore

BACKGROUND: Bacillus subtilis spores can be used for presentation of heterologous proteins. Two main approaches have been developed, the recombinant one, requiring modification of bacterial genome to express a protein of interest as a fusion with spore-coat protein, and non-recombinant, based on the...

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Bibliographic Details
Published in:Microb Cell Fact
Main Authors: Potocki, Wojciech, Negri, Alessandro, Peszyńska-Sularz, Grażyna, Hinc, Krzysztof, Obuchowski, Michał, Iwanicki, Adam
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596941/
https://ncbi.nlm.nih.gov/pubmed/28899372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-017-0765-y
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