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Total Synthesis and Cytotoxicity of Leucetta Alkaloids

The total synthesis of a number of representative natural products isolated from Leucetta and Clathrina sponges containing a polysubstituted 2-aminoimidazole are described. These syntheses take advantage of the site specific metallation reactions of 4,5-diiodoimidazoles resulting in the syntheses of...

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Publicado en:Bioorg Med Chem
Autores principales: Koswatta, Panduka B., Kasiri, Sabha, Das, Jayanta, Bhan, Arunoday, Lima, Heather M., Garcia-Barboza, Beatriz, Khatibi, Nicole N., Yousufuddin, Muhammed, Mandal, Subhrangsu S., Lovely, Carl J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596918/
https://ncbi.nlm.nih.gov/pubmed/28159485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.01.024
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