Upregulation of DACT2 suppresses proliferation and enhances apoptosis of glioma cell via inactivation of YAP signaling pathway

DACT2, one of the Dact gene family members, was shown to function as a tumor suppressor. However, its function in gliomas remains largely unknown. In this study, we investigated the role of DACT2, underlying molecular mechanisms and its clinical significance in glioma patients. Downexpression of DAC...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Tan, Ying, Li, Qiu-Meng, Huang, Ning, Cheng, Si, Zhao, Guan-Jian, Chen, Hong, Chen, Song, Tang, Zhao-Hua, Zhang, Wen-Qian, Huang, Qin, Cheng, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596571/
https://ncbi.nlm.nih.gov/pubmed/28796248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.385
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