Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens

In the last years, autophagy has been revealed as an essential pathway for multiple biological processes and physiological functions. As a catabolic route, autophagy regulation by nutrient availability has been evolutionarily conserved from yeast to mammals. On one hand, autophagy induction by starv...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Fernández, Álvaro F, Bárcena, Clea, Martínez-García, Gemma G, Tamargo-Gómez, Isaac, Suárez, María F, Pietrocola, Federico, Castoldi, Francesca, Esteban, Lorena, Sierra-Filardi, Elena, Boya, Patricia, López-Otín, Carlos, Kroemer, Guido, Mariño, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596561/
https://ncbi.nlm.nih.gov/pubmed/28771229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.373
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