p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure

Hypertension-induced cardiac hypertrophy and attenuated cardiac function are the major characteristics of early stage heart failure. Cardiomyocyte death in pathological cardiac conditions is the primary cause of heart failure and mortality. Our previous studies found that heat shock factor 1 (HSF1)...

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Опубликовано в: :Cell Death Dis
Главные авторы: Huang, Chih-Yang, Pai, Pei-Ying, Kuo, Chia-Hua, Ho, Tsung-Jung, Lin, Jing-Ying, Lin, Ding-Yu, Tsai, Fu-Jen, Padma, V Vijaya, Kuo, Wei-Wen
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596536/
https://ncbi.nlm.nih.gov/pubmed/28796250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.320
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