p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure

Hypertension-induced cardiac hypertrophy and attenuated cardiac function are the major characteristics of early stage heart failure. Cardiomyocyte death in pathological cardiac conditions is the primary cause of heart failure and mortality. Our previous studies found that heat shock factor 1 (HSF1)...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Huang, Chih-Yang, Pai, Pei-Ying, Kuo, Chia-Hua, Ho, Tsung-Jung, Lin, Jing-Ying, Lin, Ding-Yu, Tsai, Fu-Jen, Padma, V Vijaya, Kuo, Wei-Wen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596536/
https://ncbi.nlm.nih.gov/pubmed/28796250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.320
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi