p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure

Hypertension-induced cardiac hypertrophy and attenuated cardiac function are the major characteristics of early stage heart failure. Cardiomyocyte death in pathological cardiac conditions is the primary cause of heart failure and mortality. Our previous studies found that heat shock factor 1 (HSF1)...

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Vydáno v:Cell Death Dis
Hlavní autoři: Huang, Chih-Yang, Pai, Pei-Ying, Kuo, Chia-Hua, Ho, Tsung-Jung, Lin, Jing-Ying, Lin, Ding-Yu, Tsai, Fu-Jen, Padma, V Vijaya, Kuo, Wei-Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596536/
https://ncbi.nlm.nih.gov/pubmed/28796250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.320
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