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Role of Rab5 in the formation of macrophage-derived foam cell

BACKGROUND: Foam cells play a key role in the occurrence and pathogenesis of atherosclerosis. Its formation starts with the ingestion of oxidized low-density lipoprotein (oxLDL). The process is associated with Ras related protein in brain 5 (Rab5) which plays a critical role in regulating endocytosi...

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Detalhes bibliográficos
Publicado no:Lipids Health Dis
Main Authors: Chan, Lokwern, Hong, Jin, Pan, Junjie, Li, Jian, Wen, Zhichao, Shi, Haiming, Ding, Jianping, Luo, Xinping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596464/
https://ncbi.nlm.nih.gov/pubmed/28899395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-017-0559-6
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