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In vivo chemotherapeutic insight of a novel isocoumarin (3-hexyl-5,7-dimethoxy-isochromen-1-one): Genotoxicity, cell death induction, leukometry and phagocytic evaluation

Chemotherapy is one of the major approaches for the treatment of cancer. Therefore, the development of new chemotherapy drugs is an important aspect of medicinal chemistry. Chemotherapeutic agents include isocoumarins, which are privileged structures with potential antitumoral activity. Herein, a ne...

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書目詳細資料
發表在:Genet Mol Biol
Main Authors: de Araújo, Flávio Henrique Souza, de Figueiredo, Débora Rojas, Auharek, Sarah Alves, Pesarini, João Renato, Meza, Alisson, Gomes, Roberto da Silva, Monreal, Antônio Carlos Duenhas, Antoniolli-Silva, Andréia Conceição Milan Brochado, de Lima, Dênis Pires, Kassuya, Candida Aparecida Leite, Beatriz, Adilson, Oliveira, Rodrigo Juliano
格式: Artigo
語言:Inglês
出版: Sociedade Brasileira de Genética 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596378/
https://ncbi.nlm.nih.gov/pubmed/28898353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1678-4685-GMB-2016-0316
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