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Bumetanide As a Candidate Treatment for Behavioral Problems in Tuberous Sclerosis Complex

BACKGROUND: Recent studies indicate excitatory GABA action in and around tubers in patients with tuberous sclerosis complex (TSC). This may contribute to recurrent seizures and behavioral problems that may be treated by agents that enhance GABAergic transmission by influencing chloride regulation. C...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Vlaskamp, Chantal, Poil, Simon-Shlomo, Jansen, Floor, Linkenkaer-Hansen, Klaus, Durston, Sarah, Oranje, Bob, Bruining, Hilgo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596068/
https://ncbi.nlm.nih.gov/pubmed/28943860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00469
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